An improved way to detach cells from culture surfaces

Anchorage-dependent cells are cells that require physical attachment to a solid surface, such as a culture dish, to survive, grow, and reproduce. In the biomedical industry, and others, having the ability to culture these cells is crucial, but current techniques used to separate cells from surfaces can induce stresses and reduce cell viability.“In the pharmaceutical and biotechnology industries, cells are typically detached from culture surfaces using enzymes — a process fraught with challenges,” says Kripa Varanasi, MIT professor of mechanical engineering. “Enzymatic treatments can damage delicate cell membranes and surface proteins, particularly…

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